Leigh say they will have no choice but to rotate their squad as they face three games in nine games - starting with Leeds in the Tetley’s Challenge Cup quarter finals on Friday.
Paul Rowley’s side have won 16 games in a row - a club record - but the club’s director of rugby Derek Beaumont has hinted Leigh won’t send their first choice 17 to Headingley.
Instead, the Centurions will make the Kingstone Press Championship games against Halifax and Barrow their priority.
Beaumont said: “This weekend will serve as a timely rest for some players to re-energise and focus on the hard yards ahead to the finish line.
“Given the intensity and importance of league standings in this transitional season for the Championship, we must place our focus on this aspect of our season as it is paramount to the club’s long-term future.
“We have a large squad this season and playing three games in nine days will no doubt give Paul the opportunity to look at various individuals and permutations.
“I know our young boys are excited at the moment and they too should be commended along with reserves coach Paul Anderson, as the Centurions Reserves team is also unbeaten this season.”