Mum-of-three, Irene Parkinson, 68, was first diagnosed with non Hodgkin's lymphoma - a cancer of the lymphatic system - in 1999 after discovering a lump in her neck.
Irene, a director of Moorhouse's Brewery had to undergo surgery at The Christie based in South Manchester to have it removed.
Years went by and Irene felt lucky to have had no other problems until October last year when she was on a weekend away with friends.
She said: "I went to the doctors and had a biopsy, only to be delivered the bad news - the cancer had returned. .
"I was told this time I would need treatment so I was preparing myself to go through having to lose my hair."
However Irene was asked if she wanted to take part in a clinical trial. The clinical trial Irene took part in was with the revolutionary treatment called radioimmunotherapy or 'Magic Bullet.'
"I can't believe how lucky I was to take part in this. It's called the magic bullet and it was certainly magic for me. I hardly had any side effects and it meant I didn't have to lose my hair.
Irene, who has four grandchildren, has recently handed over a cheque to The Christie for £2,000 after organising a golf day at Standish golf course. The money raised will go towards lymphoma research at the cancer centre.